Untreated, adrenal insufficiency is fatal, and indeed this was invariably the case until the advent of synthetic cortisone in 1949. Treatment of Addison's disease is lifelong. The prognosis for any patient with adrenal insufficiency will depend on the underlying cause. In those patients in whom the prognosis is not affected by the underlying pathology, replacement therapy should result in a return to health. However, a Norwegian study found an excess of mortality in patients diagnosed with Addison's disease at a young age, associated with acute adrenal failure, infection and sudden death. [ 16 ]
In the ., the most common cause (about 75%) of primary adrenal insufficiency in adults is an autoimmune process. It may occur with other autoimmune conditions that affect other glands, such as the thyroid. The rest of the time, Addison disease is due to other causes, such as tuberculosis , a common cause in areas of the world where tuberculosis is more prevalent , other chronic infections, especially fungal infections , bleeding into the adrenal glands ( hemorrhage ) and the spread of cancer into the adrenal glands. Rarely, it may be due to a genetic abnormality of the adrenal glands.
Thank you Lisa for the informative article. I’m new with the ADI, starting with Cortisol AM, . PM
I’m taking HC 20mg am
5mg PM. I’m not positive but I believe the ADI started from getting Cortisone injections for Chronic back pain, over a period of 10yrs. Injections at L-4-5 levels, SI Joints, Sciatic, Hip and knees. They do help controlling pain for sure.
I’ve never been told that these have or Could cause the condition so I was wondering in your research, if you’ve seen any studies concerning this type of cause