It should be noted that in theory if one was to consistently suppress your natural estrogen levels for a long period of time, this would negatively impact your health, including your cholesterol. Due to the ability of Letrozole- to inhibit estrogen so much, this should definitely be a concern to most users. However the research that has focused on the relationship between use of letrozole and cholesterol levels is rather inconsistent in it's findings. Many studies have concluded that the compound is detrimental to both a user's HDL and LDL cholesterol levels, while other research has found no link. Obviously individuals are best served to monitor their cholesterol while using any compound via blood tests however barring that, letrozole should simply not be run for extended periods of time if at all possible. Doing so could cause serious medical complications.
Along with the issues related to blood lipids is the fact that many users complain that their libido is dramatically reduced when using the compound. This is related to the fact that estrogen is partly responsible for the regulation of an individual's sex drive. Since Letrozole- is so potent it can often drive estrogen levels too low and this inhibits a user's libido. To avoid this users can lower dosages, but some anecdotally report that even extremely low doses of the drug can cause problems. If this is the case a less potent compound such as exemestane or anastrozole may be a more appropriate option.
The Stanozolol hormone can be one of the few anabolic androgenic steroids women can use safely; while it is not the absolute mildest in nature for a woman it is up high on the list. Issues regarding the steroids hepatic nature as well as its effects on lipid profiles remain the same with women but the female athlete must also necessarily be aware of virilization. For the female athlete, the Winstrol side effects revolving around virilization will be the most concerning as such effects can destroy a womans femininity. Common virilization effects include a deepening of the vocal chords, body-hair growth and enlargement of the clitoris. The majority of women who supplement with the Stanozolol hormone, if they keep the dose low and use for very short periods will be fine. If you are a female Winstrol user and you begin to notice virilization symptoms simply discontinue use and you will be fine; nothing will change. It is when the symptoms are ignored, use is continued and the symptoms are allowed to set in that many women develop a problem; remember, man or woman responsible use is always your best friend.