The First day's bike ride was a mear 12 miles but on the second day it was 30 miles of rough terrain, switch backs, jumps, and wet rocks. I took my fall too. That evening after soaking my kiester in the hotel jacuzzi I walked tall knowing that I had finished the 30 miles but with special pride for those heroes who carry an extra burden and had all finished before me. Nonetheless, Andrew and I had our photos with the Bushs and then beyond belief were seated at his table with 5 of his other guests including; Joanna and Chip Gaines, and
Measurements of levels of 17α-OHP are useful in the evaluation of patients with suspected congenital adrenal hyperplasia as the typical enzymes that are defective, namely 21-hydroxylase and 11β-hydroxylase , lead to a build-up of 17α-OHP. In contrast, the rare patient with 17α-hydroxylase deficiency will have very low or undetectable levels of 17α-OHP. 17α-OHP levels can also be used to measure contribution of progestational activity of the corpus luteum during pregnancy as progesterone but not 17α-OHP is also contributed by the placenta .
Benzodiazepines may influence neurosteroid metabolism by virtue of their actions on translocator protein (TSPO; "peripheral benzodiazepine receptor").  The pharmacological actions of benzodiazepines at the GABA A receptor are similar to those of neurosteroids . Factors which affect the ability of individual benzodiazepines to alter neurosteroid levels may depend upon whether the individual benzodiazepine drug interacts with TSPO. Some benzodiazepines may also inhibit neurosteroidogenic enzymes reducing neurosteroid synthesis.