Corticosteroids, including prednisone, are a class of powerful drugs that reduce inflammation and suppress the immune system. They are prescribed for a wide variety of conditions, including rheumatoid arthritis (RA) and lupus, as well as multiple sclerosis, some types of cancer, asthma and skin rashes – including those caused by poison ivy. They can be prescribed short-term – until a rash clears up or until another drug can take effect, for example – or they may be used long-term. Corticosteroids come in skin creams, injections and inhaled forms; however, this study examined only people who took them orally.
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Use of QVAR with a spacer device in children less than 5 years of age is not recommended. In vitro dose characterization studies were performed with QVAR 40 mcg/actuation with the OptiChamber and AeroChamber Plus ® spacer utilizing inspiratory flows representative of children under 5 years old. These studies indicated that the amount of medication delivered through the spacing device decreased rapidly with increasing wait times of 5 to 10 seconds as shown in Table 2. If QVAR is used with a spacer device, it is important to inhale immediately.