Treating steroid induced mania

DHEA is a naturally occurring androgen produced by the adrenal glands. It is abundantly found in plasma and brain tissue and is the precursor of many hormones produced by the adrenals. DHEA seems to alleviate some of the effects of aging, such as fatigue and muscle weakness. Levels of DHEA may be lower in depressed patients, while supplementation with DHEA may reduce symptoms. However, since DHEA is a hormone, you should not take it without having your doctor check your blood level of the hormone. Also check with your physician before adding it to your diet if you are on an antidepressant, a thyroid medication, insulin, or estrogen.

  The active ingredient of Efudix is 5-Fluorouracil which is a form of chemotherapy drug.  Abnormal (pre-cancerous or cancer) cells will selectively absorb Efudix allowing the drug to kill the abnormal cells.  The treatment will produce a skin reaction that typically develops over the first week of treatment with redness and slight scaling.  Over the second week the reaction intensifies with increasing redness and crusting with resolution of the reaction occurring several weeks following cessation of treatment. A stronger reaction will be observed in those who have a greater number of abnormal cells in the skin. It is important not to stop the treatment because of the reaction. Efudix is highly effective in treating AKs, particularly when large areas of skin are affected.  Repeated treatments may be required and this is perfectly safe.

Up to 50 percent of women will experience female pattern hair loss during their lifetime. 1 Patients usually present with hair thinning over the central area of the scalp and widening of the midline part, but with reservation of the frontal hairline ( Figure 3 ). Women who also have abnormal menses, history of infertility, hirsutism, unresponsive cystic acne, virilization, or galactorrhea should have a targeted endocrine work-up for hyperandrogenism (., testosterone, dehydroepiandrosterone sulfate, and prolactin), although most will have normal androgen levels. 29 Evaluation for iron deficiency, thyroid disease, and syphilis (a rare cause) should be considered because they can contribute to hair thinning or generalized hair loss.

Glucocorticoid therapy is associated with an appreciable risk of bone loss, which is most pronounced in the first few months of use. In addition, glucocorticoids increase fracture risk, and fractures occur at higher bone mineral density (BMD) values than occur in postmenopausal osteoporosis. The increased risk of fracture has been reported with doses of prednisone or its equivalent as low as to mg daily [ 1 ]. Thus, glucocorticoid-induced bone loss should be treated aggressively, particularly in those already at high risk for fracture (older age, prior fragility fracture). In other individuals, clinical risk factor and bone density assessment may help guide therapy. The prevention and treatment of glucocorticoid-induced bone loss will be reviewed here. The clinical features are reviewed separately. (See "Clinical features and evaluation of glucocorticoid-induced osteoporosis" .)

Treating steroid induced mania

treating steroid induced mania

Glucocorticoid therapy is associated with an appreciable risk of bone loss, which is most pronounced in the first few months of use. In addition, glucocorticoids increase fracture risk, and fractures occur at higher bone mineral density (BMD) values than occur in postmenopausal osteoporosis. The increased risk of fracture has been reported with doses of prednisone or its equivalent as low as to mg daily [ 1 ]. Thus, glucocorticoid-induced bone loss should be treated aggressively, particularly in those already at high risk for fracture (older age, prior fragility fracture). In other individuals, clinical risk factor and bone density assessment may help guide therapy. The prevention and treatment of glucocorticoid-induced bone loss will be reviewed here. The clinical features are reviewed separately. (See "Clinical features and evaluation of glucocorticoid-induced osteoporosis" .)

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